Led by Dr. Yu Yuanyuan (left), our project "An aptamer drug targeting sclerostin loop3 for bone anabolic therapy without increasing cardiovascular risk" received Silver Medal at the 2023 Geneva International Exhibition of Inventions. The Geneva International Exhibition of Inventions is an annual global event where more than 1,000 inventions from all around the world are evaluated by a panel of professional judges.
Osteoporosis is a metabolic disease which leads to a reduction in bone density. Our research team designed a specific aptamer targeting sclerostin loop3 as a treatment for osteoporosis, and it effectively inhibits sclerostin’s antagonistic effects, thus promoting bone formation in osteoporotic animal models. It did not increase the risk of developing cardiovascular diseases.
Professor Sun Dong, Secretary for Innovation, Technology and Industry of the HKSAR Government (middle) visits HKBU's booth at the 48th International Exhibition of Inventions of Geneva.